Distinct characteristics of multisystem inflammatory syndrome in children in Poland

Distinct characteristics of multisystem inflammatory syndrome in children in Poland

Blog Article

Abstract During the winter months of 2020/2021 a wave of multisystem inflammatory syndrome in children (MIS-C) emerged in Poland.We present the results of a nationwide register aiming to capture and characterise MIS-C with a focus on severity determinants.The first MIS-C wave in Poland was notably high, hence here our analysis involved 274 children.The group was 62.8% boys, with a median age of 8.

8 years.Besides one Asian, all were White.Overall, the disease course was not as severe as in previous reports, however.Pediatric intensive care treatment was required for merely 23 (8.4%) of children, who were here older and exhibited a distinguished clinical picture at hospital admission.

We have also identified sex-dependent differences; teenage boys more often had cardiac involvement (decreased ejection fraction in 25.9% vs.14.7%) and fulfilled macrophage activation syndrome definition (31.0% vs.

15.2%).Among all boys, those hospitalized in pediatric intensive care unit were significantly older (median 11.2 vs.9.

1 years).Henceforth, while ethnicity and sex may affect MIS-C phenotype, management protocols might be not universally applicable, and should rather be adjusted to the specific population.